28 markers built around active GLP-1 monitoring — A1c, insulin, full lipids, liver, vitamin D, B12 — reported against their reference ranges. The focused check between annual full panels.
Elsewhere $150–$350
Next: a medical intake that takes about a minute or two, then a U.S.-licensed physician reviews and releases your lab order. You are not charged until it is approved.
Six questions every GLP-1 patient carries between checkups. Every one gets answered with a single draw.
You can't feel A1c shift day to day. Without a measurement, you're guessing.
Cholesterol, triglycerides — all silent. No symptoms until something's wrong.
Liver enzymes can drift through major weight changes — flying blind is how you miss it.
Lower food intake on a GLP-1 means more risk of B12 and Vitamin D drift. No way to know without a measurement.
Kidney function quietly declines through years of metabolic stress before symptoms show.
Rapid weight loss can affect total protein and albumin status. No symptoms until late.
Scroll, or tap the pill above to snap.
You're considering sema or tirz and want a focused starting read — A1c, insulin, lipids, liver, vitamins — so your physician has the numbers that matter before you begin therapy.
You're on therapy and your physician wants the 90-day or 6-month re-check. The 28 markers that get watched between annual full panels — metabolic, lipids, liver, micronutrients.
You've titrated down or paused therapy and want to confirm your gains are holding. A1c, insulin, lipids, liver — the markers that tell you the changes are stable.
Every marker shows up with the range it is measured against, so you can see what to act on first. Here's a glimpse of the actual report layout.
22 of 28 markers inside their reference range. 2 in standard range. 1 (Vitamin D) flagged for low-end follow-up. Full marker list below.
26 ng/mL — on the lower end of standard reference. Common in patients eating less on a GLP-1. Worth a physician conversation about supplementation and a re-check at your next 90-day draw to keep it in range.
Explained with the free OPTML Lab Decoder
Illustrative sample report. Your actual report shows your numbers across all 38 markers with the reference range each one is measured against. The Optimization score shown comes from the free OPTML Score tool, not from the lab report.
Run the GLP-1 Comprehensive Panel every 90 days and your therapy starts telling a story. Four examples — across metabolic, lipids, liver, and vitamins — of what tracking commonly looks like on therapy.
6.2 → 5.1% On therapy
142 → 94 mg/dL 4-year trend on therapy
42 → 22 U/L 4-year trend on therapy
22 → 48 ng/mL With supplementation
Illustrative tracking pattern across four representative markers. Trends shown reflect the patient's lifestyle and protocol interventions — the Optimized Health Panel measures biomarkers; it does not directly affect them. Individual results vary. Educational reference only.
Tap any marker to read what it measures and what your result means. Bundles (Comprehensive Metabolic Panel + Standard Lipid Panel) expand to show every individual biomarker.
Included in the Standard Lipid Panel.
CMP-derived liver enzymes + standalone GGT.
Included in the Comprehensive Metabolic Panel.
Included in the Comprehensive Metabolic Panel.
Quest or LabCorp draw
3,800+ U.S. draw sites. Walk-ins accepted at most.
Physician-ordered
A U.S.-licensed physician reviews your intake and orders the panel. They do not review your results.
2–3 day turnaround
Results delivered within 2–3 business days of your draw.
HSA / FSA eligible
Cash-pay. No insurance billing. HSA/FSA cards accepted.
Pick your panel and check out in under a minute. We email a lab requisition you can bring to any Quest or Labcorp patient service center nationwide, outside Hawaii and North Dakota.
Walk into one of 3,800+ locations in our lab network. The blood draw itself takes about ten minutes.
Every marker, with the reference range for each one. Delivered to your secure patient portal.
Walk into any Quest or Labcorp patient service center. Drop your ZIP and we’ll show you the real ones nearest you.
Elsewhere $150–$350
$99
One-time. No membership. No insurance. All-inclusive.
Next: a medical intake that takes about a minute or two, then a U.S.-licensed physician reviews and releases your lab order. You are not charged until it is approved.
2–3 day turnaround · Cash-pay · Cancel before draw for full refund
For patients who want the deepest possible view across every body system — heart, hormones, thyroid, inflammation, metabolism, longevity composites, heavy metals — we built The Apex Panel. The right call if you want to see everything, not just what's most relevant right now.
Different jobs. Many patients run a focused panel like this one annually and the Apex Panel every two to three years as a deep-dive baseline.
Explore the Apex PanelWhen your results land
A physician orders your panel. They do not review your results. Your report comes straight back to you, listing every marker with the reference range it is measured against.
The OPTML Lab Decoder is how you make sense of it. It explains what each marker is, what moves it, and which combinations are worth raising with a physician. Paste your report in and it reads the numbers for you.
Educational only. It does not diagnose anything, it does not replace a physician, and your laboratory remains the one that decides what falls inside its reference range.
Open the Lab Decoder →Your full lab report, usually in 2 to 3 business days, listing every marker with the reference range it is measured against. A U.S.-licensed physician reviews your intake and orders the panel. They do not review or interpret your results, so the report comes straight back to you to read. The free Lab Decoder explains what every marker means.
The lab report gives you the reference range for every marker. To go further, use the free tools on this site: the OPTML Score grades your numbers against optimal ranges, the Lab Decoder takes every marker on your panel and explains what each one is, what moves it, and which combinations are worth raising with a physician, and the biomarker library covers every marker on the panel.
Run annually, this panel works as a baseline. If you're starting a protocol (TRT, GLP-1, hormone therapy), running it pre-protocol and again 90 days in is a common pattern.
Any location in our lab network, about 3,800 nationwide: Quest and Labcorp, plus BioReference in New York and New Jersey. Not Hawaii or North Dakota, where the network has no location. We do not offer at-home or mobile blood draws. In New York and New Jersey, BioReference is available as well. Walk-ins accepted at most. We send the requisition electronically the moment you order.
The Comprehensive Metabolic Panel covers your liver (ALT, AST, bilirubin, alkaline phosphatase), kidneys and electrolytes (BUN, creatinine, eGFR, sodium, potassium, chloride, CO₂, calcium), protein status (total protein, albumin, globulin, A/G ratio), and fasting glucose.
No. This panel is cash-pay only — no insurance billing, no copay reconciliation, no surprise charges. HSA and FSA cards are accepted.
It's a 28-marker blood panel for people actively on a GLP-1. It covers metabolic, heart and lipid, liver, kidney, protein, and vitamin markers from a single blood draw at Quest or LabCorp. It's $99, one time.
Being on a GLP-1 can affect your metabolic, nutritional, and organ markers over time, so tracking them helps your physician see how you're responding and adjust your care as needed. Ongoing lab monitoring is a normal part of any therapy. Individual needs vary.
No. Lab results are educational and do not diagnose or treat anything on their own. Your own physician interprets them in the context of your full health picture. Not sure which panel fits you? Take the 60-second quiz.
This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion. Reference ranges vary by laboratory; individual results should be interpreted by your physician in the context of your overall health profile. Sample report values shown above are illustrative.
OPTML offers compounded semaglutide and tirzepatide, prescribed and overseen by U.S.-licensed physicians. Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. OPTML is not associated with, endorsed by, or affiliated with the manufacturers of FDA-approved branded weight-loss medications, and does not sell or supply those branded products. Anyone interested in an FDA-approved branded medication should consult a licensed healthcare provider or pharmacist. Individual results vary; no specific result is promised, and weight management requires ongoing medical guidance.
The whole picture in one sitting: who it suits, what the labs decide, what the first year actually looks like. Every clinical claim is cited.
How to protect lean mass while losing weight on a GLP-1.
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