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OPTML is a physician-led telehealth practice focused on hormone optimization, GLP-1 weight management, and longevity protocols. We pair compounded medications (prepared by FDA-registered 503A pharmacies) with ongoing physician oversight from licensed U.S. providers, shipped directly to you in all 50 states.

Yes. Telemedicine services are provided by Telegra MD, a U.S. physician-led telehealth services provider. Every patient is reviewed by a licensed U.S. physician who is responsible for prescribing and ongoing care. OPTML is LegitScript Certified as a healthcare merchant.

Licensed U.S. physicians within the Telegra MD network. The same physician reviews your intake, your labs (or orders new ones), determines whether you're a candidate, and remains your provider for ongoing dose titration and messaging.

All 50 states. See our state-by-state availability page for state-specific information including local fulfillment timelines and licensing.

Three meaningful differences: (1) Flat retail pricing — your monthly cost doesn't change as your dose increases. (2) Physician oversight included — not separately billed. (3) A muscle-preservation wedge: every GLP-1 patient receives a custom meal plan and physician guidance specifically designed to protect lean mass during weight loss, addressing the documented muscle loss in clinical GLP-1 trials.

OPTML was founded by Ryan Fischer, a fitness and longevity practitioner who built the business around the gap he saw between mass-market telehealth (medication-only, no follow-through) and high-end concierge medicine ($10k+ per year). See the About page for the full story.

Three steps: (1) Complete the free assessment — about 4 minutes. (2) A U.S.-licensed physician reviews your intake and (if appropriate) lab work, then designs your protocol. (3) Your medication ships in 2–3 days in temperature-controlled discreet packaging. No charge until the physician confirms you qualify.

It depends on the protocol. TRT, HRT, NAD+ and sermorelin typically require baseline labs. GLP-1 weight management can usually start without new labs if you have recent results within 12 months. If you don't have labs, your provider can order them through any Quest or Labcorp in the country.

The initial questionnaire takes about 4 minutes. Physician review is usually completed within 24 hours; if labs are needed, your timeline depends on when you can get blood drawn (typically a few days at any Quest or Labcorp).

If your physician determines a protocol isn't right for you, you are not charged. We'll explain the reason and (when applicable) point you to alternative protocols you may qualify for. Eligibility is confirmed before any billing.

No. OPTML is cash-pay; we don't bill insurance. All pricing is flat and includes the medication, supplies, and physician oversight. HSA and FSA cards are accepted.

Patients must be 18 or older. Some protocols (e.g., TRT, HRT) have additional clinical criteria your physician will review at intake.

Weight management: Semaglutide, Tirzepatide, Microdose GLP-1. Men's hormones: TRT, Enclomiphene. Women's hormones: HRT, Estradiol, Progesterone. Peptides & longevity: Sermorelin, NAD+. Stacks: High-Performer Stack (Tirz+Sermorelin), The Longevity Stack (NAD+ + Sermorelin). Lab work: The Apex Panel and other physician-ordered panels.

TRT directly replaces testosterone via weekly subcutaneous or intramuscular injection. Fast, predictable, but typically suppresses your body's own production and reduces fertility. Enclomiphene is an oral tablet that stimulates your own testosterone production by acting on the HPG axis. Slower and gentler, but preserves fertility. See the full comparison article.

Both are GLP-1-class medications for weight management. Semaglutide (the active ingredient in Ozempic/Wegovy) acts on GLP-1 receptors and produces about 15% body weight loss at the highest dose. Tirzepatide (the active in Mounjaro/Zepbound) acts on both GLP-1 and GIP receptors and produces roughly 20% weight loss. Your physician will recommend based on your starting BMI, prior history, and goals..

Sub-clinical doses of semaglutide or tirzepatide for metabolic optimization — not significant weight loss. Targeted at lean, already-fit patients who want the cardiometabolic upside (insulin sensitivity, anti-inflammation, food-noise reduction) without dramatic appetite suppression. Learn more.

A GHRH analog — a peptide that acts on the pituitary to support the body's own pulsatile growth-hormone release (not exogenous HGH). Used as a longevity/recovery protocol. Daily subcutaneous injection at bedtime. Compounded sermorelin is not FDA-approved. Full details.

Compounded nicotinamide adenine dinucleotide injected subcutaneously to support cellular co-factor availability that declines with age. Many patients pair NAD+ with sermorelin in The Longevity Stack. Compounded NAD+ is not FDA-approved. Full details.

A women's hormone restoration protocol pairing bioidentical 17β-estradiol with micronized progesterone, calibrated to your labs and titrated by your provider. For perimenopause and menopause. Full details — also available as estradiol alone or progesterone alone.

Compounded tirzepatide + compounded sermorelin under one physician-led protocol. GLP-1 for fat loss, sermorelin for sleep, recovery, and lean-mass preservation during the deficit. $499/month all-inclusive. Full details.

Compounded NAD+ + compounded sermorelin under one physician-led protocol. Cellular energy from NAD+, deeper sleep and recovery from sermorelin's GH-axis support. $349/month all-inclusive (saves $19/mo vs. ordering separately). Full details.

OPTML's flagship blood panel: 160+ biomarkers across 12 organ systems in a single blood draw. One-time $599, no subscription required. Comprehensive enough to baseline before any protocol. Full details.

Weight management: Semaglutide $249/mo, Tirzepatide $349/mo, Microdose GLP-1 $199–$299/mo. Men's hormones: TRT $199/mo, Enclomiphene $129/mo. Women's hormones: HRT Bundle $199/mo, Estradiol $99/mo (tablet) or $229/mo (cream), Progesterone $79/mo. Peptides & longevity: Sermorelin $189/mo, NAD+ $179/mo. Stacks: High-Performer Stack $499/mo, Longevity Stack $349/mo. Lab panels: Apex Panel $599 one-time, Optimized Health Male/Female $199–$229. See the full pricing page.

Everything. Your monthly price covers the compounded medication, all syringes / needles / alcohol pads / sharps container, ongoing physician oversight via provider messaging, dose titration, free 2–3 day discreet shipping. No hidden fees. No separate membership. Just your OPTML protocol.

No. Lab panels are the only separate add-on (and are clearly priced). Otherwise everything is bundled into one flat monthly retail.

For NAD+ and Sermorelin: yes. NAD+ is $179/mo monthly or $489 every 3 months (saves $48 over 3 months). Sermorelin is $189/mo monthly or $499 every 3 months (saves $68 over 3 months). For other protocols, pricing is flat monthly.

Yes. All prescription products and lab panels qualify under HSA and FSA rules as eligible medical expenses. You can use your HSA/FSA card directly at checkout.

Yes. No contracts. Cancel or pause your subscription anytime from your patient portal. Refunds for unshipped medication are issued per OPTML's standard policy.

No. OPTML uses flat retail at every dose for our subscription protocols. As your provider titrates you up, your monthly price stays the same.

Compounded medications are prepared by 503A pharmacies under a valid physician prescription, using the same active pharmaceutical ingredient as the brand product. They are not FDA-approved. The compounded preparation pathway is what makes the price difference possible. Full article on the comparison.

You complete a ~4-minute medical history and goals questionnaire. A licensed U.S. physician reviews your answers (and any labs). If you're a candidate, the physician designs your protocol, e-signs a prescription, and the compounded medication is dispensed by a 503A pharmacy partner and shipped to you within 2–3 business days.

Physician review is typically within 24 hours of intake submission. From prescription approval to medication delivery is usually 2–3 business days. End-to-end from sign-up to first injection is most commonly 3–5 days when no new labs are needed.

Yes. Unlimited provider messaging is included in every protocol's monthly price. You can ask dose questions, report side effects, request titration changes, etc.

Titration is the gradual adjustment of your dose to the level where you get the best response with the fewest side effects. For GLP-1s, this typically means starting at the lowest dose and incrementally moving up every 4 weeks. Your provider directs each step based on your response and tolerance.

Refills ship automatically each cycle based on your prescription. You don't need to call in or re-submit anything. You can pause, change dose, or cancel from your patient portal anytime.

Each shipment includes pre-filled supplies and a step-by-step injection guide. For GLP-1s the standard route is subcutaneous (under the skin, abdomen or thigh) using a small insulin-grade syringe. Your provider walks you through it; many patients describe it as essentially painless after the first attempt.

Use the 30-second panel finder — two questions and we match you to the right panel for your goal. Quick guide: Apex Panel ($599) = the most complete picture (160+ markers). Optimized Health, Male ($199) / Female ($229) = the standard starting panel. TRT Panel ($75) = focused titration markers for men on testosterone. GLP-1 Comprehensive ($99) = metabolic markers for patients on semaglutide or tirzepatide.

At any Quest Diagnostics or Labcorp location nationwide (2,200+ draw sites). No appointment needed. Walk in with your physician-ordered requisition; in and out in about 15 minutes.

Most panels return within 3–5 business days from draw. You'll receive every marker with normal-range context plus a physician-reviewed summary — not just a portal full of numbers.

Often yes — labs within the past 12 months are usually accepted, depending on the protocol. Upload them at intake and your physician will confirm whether new labs are needed.

All medications carry some risk, which is why every patient is reviewed by a licensed physician before prescription and monitored throughout. Compounded medications are prepared by FDA-registered 503A pharmacies under USP <797> sterility standards. Side-effect profiles for each protocol are described on the individual product pages. Information on this site is for educational purposes and is not medical advice — your physician's clinical judgment governs your specific care.

A compounded preparation is a medication prepared by a licensed compounding pharmacy (503A) for a specific patient under a valid physician prescription, using the same active pharmaceutical ingredient as a brand product. Compounded medications are not FDA-approved. The FDA does not verify the safety, effectiveness, or quality of compounded drugs.

Depends on the protocol. GLP-1s: nausea, constipation, decreased appetite, fatigue — typically mild and tied to dose titration. TRT: increased hematocrit, acne, possible mood changes. HRT: breast tenderness, breakthrough bleeding (first cycles). Sermorelin: injection-site reactions, occasional drowsiness near bedtime. NAD+: transient warmth or flushing at the injection site. See each individual product page for the full side-effect profile.

For any new or unusual symptoms, missed doses, questions about dosing, or before starting another medication. Message your OPTML provider directly through the portal. For emergencies, call 911 or your local emergency services. The patient portal is not for urgent care.

The active pharmaceutical ingredients used in our compounded preparations are the same as those used in FDA-approved branded products. However, compounded preparations themselves are not FDA-approved. The FDA does not verify the safety, effectiveness, or quality of compounded drugs. Compounded preparations dispensed through OPTML are prepared by FDA-registered 503A pharmacies under USP <797> sterility standards.

Yes. OPTML is a LegitScript Certified Healthcare Merchant. LegitScript verifies that healthcare and pharmacy merchants meet legal and regulatory standards.

Yes. Patient information is handled in compliance with HIPAA. See our HIPAA Notice of Privacy Practices for details on how protected health information is collected, used, and disclosed.

Telegra MD is the U.S. physician-led telehealth services provider that powers OPTML's clinical operations. Licensed physicians within the Telegra MD network conduct intake review, prescribing, and ongoing care.

A 503A pharmacy is a state-licensed, FDA-registered compounding pharmacy that prepares medications for individual patients under valid physician prescriptions, following USP <797> sterility standards. OPTML's compounded medications are dispensed by 503A partners including Strive, Boothwyn, and Absolute.

Free 2–3 business day shipping nationwide. Once your prescription is approved by your physician, your medication leaves the 503A pharmacy in insulated, temperature-controlled, plain packaging.

Yes. All shipments use plain outer packaging with no medical branding visible.

Refrigerate the vial after first reconstitution. Full storage and handling instructions ship with every kit. Each vial is stable for the period specified in your dispensing label.

Contact support at info@optml.com with your order number. We'll trace the package and replace if needed.

From your patient portal — there's a cancel option on your subscription page. No call required, no retention script. You can also pause your subscription if you want to take a break without canceling entirely.

Refunds for unshipped medication are issued per OPTML's standard policy. Medication that has already shipped cannot be returned for safety reasons. If you have a billing question, contact info@optml.com.

Message your provider through the patient portal. Most changes are turned around within 24 hours. For protocol switches that require new labs, your provider will order them.

From the billing section of your patient portal. HSA/FSA cards are accepted.

Email info@optml.com. For clinical questions, message your physician directly through the patient portal. The OPTML Assistant can also answer most common questions instantly.

A curated Q&A assistant available from the floating chat bubble on every page of optml.health. It answers common questions about OPTML's products, pricing, intake process, lab panels, shipping, and customer service.

The Assistant is trained only on OPTML's own website content — nothing else. It does not have access to outside medical sources, patient records, or generative AI knowledge. It is a curated library of pre-written answers authored and reviewed by the OPTML team.

No. The Assistant does not provide medical advice, diagnosis, or treatment recommendations. All clinical decisions about your care are made by a licensed U.S. physician after individual evaluation. The Assistant exists to help you find information about OPTML's products and process — for personal medical guidance, talk to your provider through the patient portal or call 911 for emergencies.

No. The Assistant does not use a generative language model. It is a curated library of pre-written responses keyed to common topics. This is by design — it ensures answers are accurate, on-brand, and bounded to information OPTML has verified.

Use the search bar at the top of this Help Center, message your physician through the patient portal for clinical questions, or email info@optml.com for account and billing questions.