Two GLP-1 protocols · One online consult

Two GLP-1s. One protocol. Choose the right fit.

Two GLP-1 molecules used in physician-supervised weight-management protocols. Semaglutide acts on the GLP-1 receptor; tirzepatide adds GIP-receptor activity for a different appetite-modulation profile. OPTML dispenses both as compounded preparations under U.S. licensed-physician prescription.

  • All-inclusive pricing — no membership fees
  • Provider-matched: tirzepatide or semaglutide
  • 503A licensed pharmacies (USP <797>) · Cancel anytime
  • Only at OPTML
    GLP-1 Muscle Loss Protocol included
    Educational guide on muscle preservation during physician-supervised GLP-1 protocols.

Includes a consultation with a U.S.-licensed physician

Compounded medication is not FDA-approved. Sema $249/mo · Tirz $349/mo · HSA/FSA eligible.

LegitScript Certified Healthcare MerchantLegitScript CertifiedHealthcare Merchant
Compounded GLP-1 vial Prescription only 4.9 · 200,000+ patients across our provider network
Physician-Prescribed Licensed Pharmacy
Weight Loss · GLP-1
★★★★★4.9 · 200,000+ patients across our provider network

Two GLP-1s. One protocol. Choose the right fit.

Tirzepatide and semaglutide are both prescribed online by U.S. licensed providers, compounded at 503A pharmacies, and shipped to your door monthly. Your provider helps you choose based on your starting weight, goals, and how your body responds.

  • All-inclusive pricing — no membership fees
  • 503A licensed pharmacies (USP <797>)
  • U.S.-licensed providers · Cancel anytime
  • GLP-1 Muscle Loss Protocol included

Starting at $249/mo · Free provider consult · HSA/FSA eligible

Weight loss with OPTML GLP-1 protocols
Step 1 of 3 · Choose your GLP-1

Tirzepatide or semaglutide? It depends on your goal.

Both are compounded GLP-1 medications, prescribed and overseen by U.S.-licensed providers. Your provider helps you choose based on your starting weight, side-effect tolerance, and clinical goals.

Most weight loss
OPTML compounded tirzepatide vial
Tirzepatide

A dual GIP / GLP-1 receptor agonist.

Acts on both GIP and GLP-1 receptors, which the literature describes as having a stronger appetite-modulation profile than GLP-1 alone. Used in physician-supervised weight-management protocols. OPTML dispenses the compounded preparation under U.S. licensed-physician prescription; compounded medications are not FDA-approved.

Start tirzepatide $349/mo · physician oversight included
Semaglutide

A GLP-1 receptor agonist.

Acts on the GLP-1 receptor: reduces hunger signaling and slows gastric emptying. Used in physician-supervised weight-management protocols. OPTML dispenses the compounded preparation under U.S. licensed-physician prescription; compounded medications are not FDA-approved.

Start semaglutide $249/mo · physician oversight included
OPTML compounded semaglutide vial
Tirzepatide · Dual-receptor

Compounded Tirzepatide

A dual GIP / GLP-1 receptor agonist used in physician-supervised weight-management protocols. Acts on two complementary appetite-regulation pathways. Compounded medications are not FDA-approved.

  • Dual receptor action (GIP + GLP-1) for stronger appetite modulation
  • Dual GIP/GLP-1 mechanism, appetite + glucose
  • Once-weekly subcutaneous injection
  • Standard titration: 2.5 → 5 → 7.5 → 10 → 15 mg
$349/mo · provider consult included
Semaglutide · GLP-1

Compounded Semaglutide

A GLP-1 receptor agonist used in physician-supervised weight-management protocols. Reduces hunger signaling and slows gastric emptying. Compounded medications are not FDA-approved.

  • Single-receptor action: GLP-1 reduces hunger + slows gastric emptying
  • Single GLP-1 receptor mechanism
  • Once-weekly subcutaneous injection
  • Standard titration: 0.25 → 0.5 → 1.0 → 1.7 → 2.4 mg
$249/mo · provider consult included

Not sure which fits? Take the 60-second protocol quiz, your provider routes you based on starting weight, goals, and tolerance.

The Rebound Cycle
80%

Roughly 8 in 10 people who lose weight through dieting alone regain it. Not because they quit. Because their biology fought back.

Wing & Phelan, Am J Clin Nutr 2005 · Sumithran et al., NEJM 2011 · Fothergill et al., Obesity 2016

How many times have you lost 10+ lbs?
Current weight 220lbs
Goal weight 180lbs
Weight you may have lost and regained
100lbs
2.5 cycles × 40 lb gap

The work was real every single time. But the body fights to keep weight on, and that pushback is biology, not a lack of discipline.

You were never the problem.
Your biology was.

And biology is something a U.S. licensed physician can measure and treat. They review your history, run your labs, and determine whether prescription treatment is appropriate for you.

Get started
Where these numbers come from

Long-term studies of dieting consistently find most lost weight is regained within 3 to 5 years (Wing & Phelan, Am J Clin Nutr 2005). After weight loss, ghrelin rises and leptin falls, and these shifts persist for at least a year (Sumithran et al., NEJM 2011). Resting metabolic rate can stay suppressed for years (Fothergill et al., Obesity 2016). Figures describe research populations and dieting in general; they are educational, not a prediction of your results or a claim about any treatment.

Step 3 of 3 · How it works

Start your GLP-1 in 4 simple steps.

Lab review, physician oversight, and medication shipped to your door, same protocol whether you choose tirzepatide or semaglutide.

01

Start your online visit

Answer a few questions about your health and goals, all online—no in-person doctor's office visit necessary.

02

Provider evaluation

A U.S.-licensed provider reviews your intake and prescribes tirzepatide or semaglutide, if appropriate.

03

Personalized plan

Compounded GLP-1, syringes, and supplies. Free discreet shipping. Titration tailored to you.

04

Ongoing support

Message your provider anytime. Dose adjustments, refills, and questions handled in-app.

9:41

Question 1 of 12

What do you want to accomplish with OPTML?

  • Lose weight
  • Energy & vitality
  • Sleep & recovery
  • Optimize hormones

 Start losing weight in 4 simple steps

  1. Start your online visit

    Answer a few questions about your health and goals, all online—no in-person doctor's office visit necessary.

  2. Provider evaluation

  3. Personalized plan

  4. Ongoing support

After you order

Expected time from order to your door.

Your medication is not sitting on a shelf waiting for you. It is prepared for you, to your prescription, after a physician has read your file — and that is the reason for the wait. Here is where every day goes.

7–10 days
from ordering to it arriving, for a straightforward protocol. Roughly 5–7 days for the physician and the pharmacy, then 2–3 days in transit.
Your online visitabout 10 minutes

Done from your kitchen table, not a waiting room. No appointment to book, no clinic to drive to, no time off work. You answer questions about your health and your goals, and that is the whole of your part in it.

A physician actually reads your filethe slow part, on purpose

A U.S.-licensed physician goes through what you submitted, and your lab work where your protocol calls for it. This is a real clinical decision made by a real person, which is why it takes days rather than minutes — and it is the step you would least want us to rush.

Some protocols need a further conversation, or bloodwork first. TRT, enclomiphene and HRT commonly do.

Your medication is made for younot off a shelf

Once a physician approves it, your prescription goes to a state-licensed, FDA-registered 503A compounding pharmacy, where it is prepared for you individually under USP <797> sterility standards.

That is what compounding means: it is made to your prescription after it is written, rather than manufactured in advance and picked from stock. It is also why this is measured in days. Compounded preparations are not FDA-approved.

It ships to your door2–3 days

Insulated and temperature-controlled, in plain packaging with no medical branding on the outside. Shipping is free and already in your price, and tracking is emailed when it leaves.

The one thing that holds an order upworth reading

An order pauses if something is still outstanding on your side — an intake form you have not finished, ID verification, or lab work. It is the most common reason an order goes quiet, and the system cannot always alert you when it happens.

So if it has been quiet for a couple of days, check your email and your patient portal before anything else. That is nearly always where the missing piece is, and clearing it starts your order moving again immediately. Full checklist here.

Ordering on a Friday or at the weekend

Orders are processed seven days a week. What is not covered at weekends is anything needing a person — a stuck form, an ID check, a question for your provider. Order late on a Friday and you will likely hear more at the start of the week.

How to check where you are

Your patient portal shows the live stage of your order. If your purchase appears there and you have the confirmation email, you are in the queue and nothing is wrong.

These are typical ranges, not guarantees, and delays do happen. Something look wrong? Email info@optml.health and a person will pick it up. For anything clinical, message your physician in the portal. For emergencies, call 911.

Our provider network

What customers across our provider network are saying

Prescribed by board-certified U.S.-licensed clinicians

Licensed in all 50 states · Meet your care team

Frequently asked questions

Semaglutide is a GLP-1 receptor agonist. Tirzepatide is a dual GIP and GLP-1 receptor agonist. The literature describes the dual mechanism as having a stronger appetite-modulation profile in some populations. Your physician helps you decide based on your starting weight, side-effect tolerance, and budget.
OPTML's compounded preparations of semaglutide and tirzepatide are made to your specific prescription by FDA-registered 503A pharmacies under USP <797> sterility standards, on prescription by U.S. licensed physicians. Compounded medications are not FDA-approved.
Yes. Many patients start on semaglutide and switch to tirzepatide if they want a stronger response or plateau. Your provider handles the transition and dose recalibration.
Both have similar GI side effect profiles, nausea, constipation, and occasional fatigue, especially during dose escalation. Tirzepatide's dual-receptor mechanism can produce slightly more pronounced GI effects in some patients. Your provider titrates slowly to minimize discomfort.
Compounded semaglutide starts at $249/mo. Compounded tirzepatide starts at $349/mo. Both include the provider consult, medication, supplies, and ongoing messaging. HSA/FSA eligible.
OPTML services all 50 states with licensed telehealth providers. Some states require additional documentation, we'll let you know during intake.

Ready to find your GLP-1?

Free consult. No insurance required. Cancel anytime. Your provider chooses the right molecule for your goals.

LegitScript Certified Healthcare MerchantLegitScript CertifiedHealthcare Merchant
LegitScript verifiedLicensed US providersHIPAA-protected503A pharmacy
Get started
Start today

Ready to find your GLP-1?

5-minute online consult. Your provider matches tirzepatide or semaglutide to your starting weight and goals. Free discreet shipping, included in your price.

  • LegitScript verified
  • Licensed U.S. providers
  • HIPAA-protected
  • 503A pharmacy
Weight-loss medication disclaimer

OPTML offers compounded semaglutide and tirzepatide, prescribed and overseen by U.S.-licensed physicians. Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. OPTML is not associated with, endorsed by, or affiliated with the manufacturers of FDA-approved branded weight-loss medications, and does not sell or supply those branded products. Anyone interested in an FDA-approved branded medication should consult a licensed healthcare provider or pharmacist. Individual results vary; no specific result is promised, and weight management requires ongoing medical guidance.

The complete GLP-1 guide

The whole picture in one sitting: who it suits, what the labs decide, what the first year actually looks like. Every clinical claim is cited.

Free guide

Unlock the free
guide to keeping muscle

How to protect lean mass while losing weight on a GLP-1.

Double-check your email. A typo means we cannot reach you or resend your guide.

We will send occasional emails you can unsubscribe from at any time. See our Privacy Policy.

From $249/mo Tirz or Sema · Cancel anytime
Get started →
Weight Loss Program Starting at$199/mo
Get started