Heart system

HDL Cholesterol

HDL-C

The cholesterol carried by HDL particles — often called 'good cholesterol.'

What is it

HDL Cholesterol — in plain English.

HDL cholesterol measures the cholesterol carried by high-density lipoprotein particles. HDL plays a role in reverse cholesterol transport, moving cholesterol away from artery walls.

Why it's measured

What HDL-C can reveal.

Higher HDL has been associated with cardiovascular protection in epidemiologic research, though the relationship is complex and HDL particle function matters alongside concentration.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

> 40 (men) / > 50 (women) mg/dL

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower HDL-C — at a high level.

Elevated

Generally considered favorable in research, though extremely high values warrant clinical interpretation.

Lower

Has been associated with elevated cardiovascular risk in published research.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When HDL-C is typically run.

Part of every standard cholesterol panel.

Related markers

Often measured alongside HDL-C.

Measured in

HDL-C is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.