NAD+ is the cofactor that powers nearly every metabolic process in your cells — energy production, DNA repair, mitochondrial health. Levels decline sharply with age. Subcutaneous NAD+ rebuilds the cellular fuel your body has lost. Prescribed by U.S.-licensed providers, shipped to your door.
Includes a consultation with a U.S.-licensed physician
Compounded medication is not FDA-approved. Starting at $179/mo · HSA/FSA eligible.
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Prescription only
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LegitScript CertifiedHealthcare Merchant
NAD+ is the molecule your mitochondria use to make energy. Levels drop ~50% by age 50, and the consequences cascade: fatigue, slower recovery, dimmer cognition, accelerated cellular aging. Restoring NAD+ restores the substrate your cells need to function.
Starting at $179/mo · Free provider consult · HSA/FSA eligible
NAD+ is a coenzyme in nearly every cell, central to energy and DNA repair. Research links aging to lower NAD+ in many tissues. Explore what it does, what affects it, and the pattern researchers see.
General educational information about NAD+ biology and how it is studied in relation to aging. Research on NAD+ and age is evolving and not fully settled: human studies of whole-blood NAD+ have produced mixed results, while direct measurements in tissues such as muscle, brain, and skin more consistently show age-related decline. The curve and percentages are illustrative of a general research pattern, not your levels, not a measurement of any individual, and not a prediction. This makes no claim about any product, medication, or supplement, and does not state or imply that anything offered on this page changes NAD+ levels. What your own status is, and whether anything is appropriate for you, is determined by a licensed physician.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell of your body. It's the molecule your mitochondria use to convert nutrients into ATP — the actual energy currency that powers everything from heartbeat to thought.
NAD+ levels drop ~50% between age 30 and 50. The consequences cascade: fatigue, slower recovery, dimmer cognition, reduced metabolic flexibility, accelerated cellular aging.
Daily subcutaneous injection. Pharmaceutical-grade NAD+ delivered directly under the skin — fastest onset, highest absorption, most reliable serum levels.
The injection is small (insulin-syringe size), virtually painless, and takes seconds to administer at home each morning.
Anyone over 35 who's noticed their baseline energy isn't what it used to be — afternoon crashes, slower recovery, "fog" that wasn't there before. Also patients pursuing longevity protocols who want mitochondrial support alongside other interventions.
NAD+ pairs naturally with TRT, HRT, and sermorelin — addressing the cellular layer that hormones and peptides depend on.
NAD+ is one of the most-studied molecules in longevity research. Documented effects include improved mitochondrial respiration, sirtuin activation, DNA repair, and metabolic flexibility. Clinical NAD+ supplementation has shown improvements in fatigue, sleep, and recovery markers in adult populations.
Sources: Verdin E, Science, 2015. Yoshino J et al, Cell Metabolism, 2018. Martens CR et al, Nature Communications, 2018.
Hormones and peptides give your body the signals. NAD+ gives it the substrate, and is commonly added alongside these protocols to support the cellular layer. Individual results vary.
No surprises, no upsells. Each shipment includes everything you need to administer safely at home, plus full clinical support.
NAD+ is among the most-studied molecules in longevity science. The numbers below reflect documented effects in human supplementation studies and adult mitochondrial-function literature.
Sources: Verdin E, Science, 2015. Yoshino J et al, Cell Metabolism, 2018. Martens CR et al, Nature Communications, 2018. Effects vary by individual.
Online assessment to your door, with free discreet shipping. No in-person visits, no waiting rooms.
Get started →Answer a few questions about your health and goals, all online—no in-person doctor's office visit necessary.
A U.S.-licensed provider reviews your intake and prescribes the right protocol, if appropriate.
Compounded NAD+, syringes, and supplies. Free discreet shipping. Protocol tailored to your goals.
Message your provider anytime. Dose adjustments, refills, and questions handled in-app.
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Start NAD+ in 4 simple steps
Answer a few questions about your health and goals, all online—no in-person doctor's office visit necessary.
No commitment. No insurance needed. See full eligibility & contraindications →
NAD+, provider oversight via call or text, all supplies, and free shipping included.
A U.S.-licensed physician personally reviews every order before anything is prescribed.
Subcutaneous NAD+ prescribed and titrated to your response. Your monthly price stays the same regardless of dose tier.
Or $489 every 3 months — flat retail at every dose.
Daily subcutaneous, dosed to your response. Patients typically take it in the morning to support the day’s energy curve.
Your monthly price includes everything.
Physician consultation, prescription, and ongoing medical oversight. No hidden fees. No separate membership. Just your optml protocol.
Billed monthly. Cancel anytime.
One shipment, billed quarterly. Cancel anytime.
Prescribed by board-certified U.S.-licensed clinicians
Licensed in all 50 states · Meet your care team
Your medication is not sitting on a shelf waiting for you. It is prepared for you, to your prescription, after a physician has read your file — and that is the reason for the wait. Here is where every day goes.
Done from your kitchen table, not a waiting room. No appointment to book, no clinic to drive to, no time off work. You answer questions about your health and your goals, and that is the whole of your part in it.
A U.S.-licensed physician goes through what you submitted, and your lab work where your protocol calls for it. This is a real clinical decision made by a real person, which is why it takes days rather than minutes — and it is the step you would least want us to rush.
Some protocols need a further conversation, or bloodwork first. TRT, enclomiphene and HRT commonly do.
Once a physician approves it, your prescription goes to a state-licensed, FDA-registered 503A compounding pharmacy, where it is prepared for you individually under USP <797> sterility standards.
That is what compounding means: it is made to your prescription after it is written, rather than manufactured in advance and picked from stock. It is also why this is measured in days. Compounded preparations are not FDA-approved.
Insulated and temperature-controlled, in plain packaging with no medical branding on the outside. Shipping is free and already in your price, and tracking is emailed when it leaves.
An order pauses if something is still outstanding on your side — an intake form you have not finished, ID verification, or lab work. It is the most common reason an order goes quiet, and the system cannot always alert you when it happens.
So if it has been quiet for a couple of days, check your email and your patient portal before anything else. That is nearly always where the missing piece is, and clearing it starts your order moving again immediately. Full checklist here.
Orders are processed seven days a week. What is not covered at weekends is anything needing a person — a stuck form, an ID check, a question for your provider. Order late on a Friday and you will likely hear more at the start of the week.
Your patient portal shows the live stage of your order. If your purchase appears there and you have the confirmation email, you are in the queue and nothing is wrong.
These are typical ranges, not guarantees, and delays do happen. Something look wrong? Email info@optml.health and a person will pick it up. For anything clinical, message your physician in the portal. For emergencies, call 911.
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5-minute online consult. Physician review. Free discreet shipping, included in your price.
LegitScript CertifiedHealthcare Merchant
5-minute online consult. Physician review. Free discreet shipping, included in your price.
Your NAD+ protocol comes with the whole system
Included free with your active NAD+ protocol. No separate membership, no add-on charges.
OPTML offers compounded semaglutide and tirzepatide, prescribed and overseen by U.S.-licensed physicians. Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. OPTML is not associated with, endorsed by, or affiliated with the manufacturers of FDA-approved branded weight-loss medications, and does not sell or supply those branded products. Anyone interested in an FDA-approved branded medication should consult a licensed healthcare provider or pharmacist. Individual results vary; no specific result is promised, and weight management requires ongoing medical guidance.
The whole picture in one sitting: who it suits, what the labs decide, what the first year actually looks like. Every clinical claim is cited.
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