Men's Health · Fertility-preserving T support

★★★★★4.9 / 200,000+ patients across our provider network

Boost your own testosterone. Keep your fertility.

Name: Testosterone Replacement Therapy (TRT) via OPTML
Brand: OPTML
Price: 199 USD
Availability: InStock

Enclomiphene is a selective estrogen receptor modulator (SERM) that signals your body to produce more of its own testosterone. No exogenous hormone, no shutdown of natural production, fertility preserved. $129/mo flat retail. Most patients see baseline T lift within 4-6 weeks.

✓ Licensed US providers✓ 2-3 day shipping✓ Cancel anytime

Start your free assessment How it works

Starting at $129/mo · HSA/FSA eligible · Cancel anytime

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Estimate your T level

Slide to compare your current total testosterone to optimal ranges.

350 ng/dL total T

1001200 ng/dL

Your Range

Low (Candidate for TRT)

Typical symptoms: fatigue, low libido, brain fog.

Reference ranges vary by lab. Always confirm with bloodwork before treatment.

Quick Answer

Testosterone Replacement Therapy (TRT) uses pharmaceutical-grade testosterone, most commonly testosterone cypionate 200 mg/mL, to restore total T to optimal range in men with biochemically confirmed low T. Typical dosing: 80-200 mg weekly via subcutaneous or intramuscular injection, calibrated to total T, free T, SHBG, and estradiol labs. Standard symptoms screened: low energy, low libido, brain fog, poor sleep, and reduced morning erections.

Source: Endocrine Society Clinical Practice Guidelines, 2018 · AUA Guidelines, 2018

Step 1 of 4 · Choose your path

TRT or enclomiphene? It depends on fertility.

OPTML offers both. Your provider helps you choose based on labs, age, and whether you want to preserve fertility now or later.

Injection

Boosts testosterone directly.

Exogenous testosterone delivered via injection to raise total T levels quickly and predictably.

Direct hormone replacement
Fastest path to optimal range
Suppresses natural T production
Not for men planning pregnancy

Oral pill

Stimulates your body's natural T.

Encourages your body to produce its own testosterone while helping preserve fertility.

Endogenous T production
Fertility-preserving
Once-daily oral capsule
Best for men under 40 or planning to conceive

Option 1 · Most popular

TRT · Direct replacement

Testosterone cypionate

Pharmaceutical-grade testosterone, weekly subcutaneous injection. Fastest, most predictable T elevation.

Total T rises within 24-72 hours of first dose
Most validated long-term safety data (TRAVERSE 2023)
Suppresses fertility — best for men done with childbearing
Standard maintenance: 80-200 mg/wk calibrated to labs

$199/mo annual

Start TRT consult

Option 2 · Fertility-preserving

Enclomiphene · Oral pill

Enclomiphene citrate

Daily oral capsule. Raises your body's own testosterone via the LH/FSH pathway — testicular function and fertility preserved.

Total T rises 200-400 ng/dL by weeks 8-12
Preserves fertility — sperm production maintained
Daily oral capsule — no needles, no cold-chain shipping
Best fit for men still planning to have children, or under 40

$129/mo · flat retail

Start your enclomiphene consult

Not sure which fits? Take the 60-second protocol quiz, it asks 4 questions about your fertility plans, age, and goals, then routes you.

What you get

Everything in your enclomiphene protocol

Pharmaceutical-grade enclomiphene citrate, a simple once-daily oral protocol, lab-driven dose calibration, and a provider behind every refill.

Enclomiphene citrate

Pharmaceutical-grade oral capsules. Dose calibrated to your labs.

Once-daily protocol

One capsule a day. No injections, no needles, no schedule juggling.

Fertility-preserving

Stimulates your body's own testosterone production while keeping sperm production intact.

Lab-based dose tuning

Bring your own labs or order through OPTML at member rates. Provider adjusts your dose to your numbers.

Provider + care messaging

Direct provider messaging. Dose adjustments handled by your physician.

Step 2 of 4 · See if you qualify

Sound like you?

Four quick questions used by clinicians to flag low-T candidates. No email required, your answers stay in your browser.

Persistent low energy or fatigue, even after sleep?

Drop in libido or sexual performance vs. years past?

Brain fog, low motivation, or mood flatness?

Sleep that no longer feels restorative, waking tired?

Stays on your device ~60 seconds HIPAA-grade pathway Reviewed by U.S. provider

Get labs + provider review

TRT is one of the most studied interventions in medicine

The TRAVERSE trial, the largest TRT cardiovascular safety study ever conducted, enrolled over 5,200 men across 316 sites.

Non-inferior

Cardiovascular safety vs. placebo

+31%

Improvement in sexual function scores

+23%

Improvement in energy and mood scores

Sources: Lincoff AM et al. NEJM. TRAVERSE Trial. 2023. Bhasin S et al. JCEM. Endocrine Society Guidelines. 2018.

How it works

Get your protocol in 5 simple steps.

From intake to first injection in 2-3 days. No in-person visits. No insurance needed.

Step 1 of 5

What are you trying to optimize?

Energy & drive

Strength & recovery

Body composition

Mood & focus

Continue →

1
Quick online intake
4-minute medical history. We screen for absolute contraindications and confirm eligibility in your state.
2
Comprehensive labs
Total T, free T, estradiol, SHBG, PSA, CBC, metabolic panel. One blood draw at any Quest or Labcorp.
3
Physician review
A licensed U.S. physician reviews your labs, symptoms, and history. Builds your protocol.
4
Discreet shipment
Enclomiphene citrate capsules in plain packaging. 2-3 day delivery.
5
Retest at week 6 & 12
Follow-up labs recommended (separate add-on at member rates). Provider adjusts dose to keep you in optimal range and safe hematocrit.

Want the full screening checklist? Read the TRT eligibility & contraindications →

What progress looks like

Track your testosterone, lab to lab.

Every OPTML TRT patient retests at week 6 and week 12. Most see total testosterone restored to optimal range within the first lab redraw.

As of today

Total Testosterone

Optimal

Illustrative trajectory based on average OPTML TRT patient. Individual results vary. Lab redraws at week 6 and week 12 are recommended; available as an add-on at member rates.

What to expect

Your typical 12-week journey on TRT

Based on aggregate clinical data and TRAVERSE trial outcomes. Individual results vary.

Week 1-2

Days 1-14

First injections, baseline lift

Most patients notice a subtle but real lift in mood and morning energy within the first two doses. Some report improved sleep quality.

Week 4

+150-300 ng/dL

Total T rises into normal range

Mid-cycle labs typically show total T moving from sub-clinical (under 350) into healthy range (500-700+). Libido and motivation start to recover.

Week 8

Steady-state

Energy, mood, and labs improve

Energy, mood, and sleep stabilize. Lab markers (free testosterone, hematocrit, estradiol) move toward optimal range. Libido and overall wellbeing improve. Provider adjusts dose if needed.

Month 3

+342 ng/dL avg

"Like myself again"

Full therapeutic effect. Most report energy, drive, body composition, and mood at levels they haven't felt in years. Quarterly labs confirm.

Source: Bhasin S et al. JCEM 2018 (Endocrine Society Clinical Practice Guidelines). TRAVERSE trial (NEJM 2023, n=5,246) confirmed cardiovascular safety of TRT in middle-aged men with hypogonadism.

Start your free assessment →

Step 4 of 4 · Start treatment

Transparent pricing. No surprises.

Physician consult, medication, and ongoing monitoring included. Labs available as a separate add-on.

LegitScript verifiedLicensed US providersHIPAA-protected503A pharmacy

Monthly

$129/month— cancel anytime

Billed monthly. Cancel anytime.

Compounded enclomiphene
Provider oversight via call or text
Free 2-3 day shipping
Cancel anytime

Start your enclomiphene consult

Best Value · Save $58

3-month supply

$110/month

$329 every 3 months. One shipment, billed quarterly. Cancel anytime.

Compounded enclomiphene
Provider oversight via call or text
Free 2-3 day shipping
Cancel anytime

Start your enclomiphene consult

Your monthly price includes everything.

Physician consultation, prescription, and ongoing medical oversight. No hidden fees. No separate membership. Just your optml protocol.

No surprises

Side effects, told straight.

TRAVERSE (NEJM 2023, n=5,246) confirmed cardiovascular safety in middle-aged men with hypogonadism. Here's what to actually expect, monitored by your provider every step.

Common >10%

Acne or oily skin (especially first month)
Mild fluid retention
Increased red blood cell count (we monitor with quarterly labs)
Injection-site discomfort

Most are mild and resolve as your hormones reach steady-state.

Less common 1-10%

Mood changes (rare with proper dosing)
Headache or sleep disturbance
Mild breast tenderness (managed with anastrozole if needed)
Reduced sperm count / fertility (consider enclomiphene if planning kids)

Tell your provider, dose adjustment or estradiol management usually fixes these.

Rare but serious <1%

Polycythemia (high hematocrit), managed with blood donation if needed
Worsening sleep apnea
Edema in patients with heart/kidney disease
Gynecomastia (with poor estradiol control)

Contraindicated

Active prostate cancer or untreated severe BPH
Active breast cancer (in men)
Hematocrit > 54%
Untreated severe sleep apnea
Trying to conceive (consider enclomiphene)

Call your provider right away if you have chest pain, severe headache, sudden vision changes, or trouble breathing. We recommend quarterly hematocrit, PSA, and estradiol monitoring. Labs are available as a separate add-on at member rates.

Source: Bhasin S et al. JCEM 2018 (Endocrine Society Clinical Practice Guidelines); TRAVERSE Trial NEJM 2023; FDA testosterone prescribing information.

Frequently asked questions

Yes, TRT requires confirmed low testosterone (typically two morning labs below 300 ng/dL, or symptomatic men with free T in the low quartile). We order a comprehensive panel including total T, free T, estradiol, SHBG, PSA, CBC, and a metabolic panel.

The TRAVERSE trial (2023), the largest cardiovascular safety study of TRT ever done, found TRT was non-inferior to placebo for major adverse cardiac events in men with hypogonadism. Proper monitoring (hematocrit, lipids, blood pressure) is essential, and OPTML handles all of it.

TRT suppresses the HPG axis and typically reduces sperm production. If fertility preservation is a priority, we offer Enclomiphene, which raises natural testosterone without suppressing fertility, or combination protocols with hCG.

We primarily prescribe testosterone cypionate as a subcutaneous or intramuscular injection, typically weekly or twice-weekly. Some patients prefer creams or pellets; speak with your physician about alternatives.

Common: acne, oily skin, mild fluid retention, mood changes early on. Less common but monitored: elevated hematocrit, high estradiol, worsened sleep apnea. Regular labs let us catch and adjust quickly.

OPTML currently services all 50 states with licensed telehealth physicians. Some states require additional documentation, we'll let you know during intake.

Boost your own testosterone. Keep your fertility.

Estimate your T level

TRT or enclomiphene? It depends on fertility.

Boosts testosterone directly.

Stimulates your body's natural T.

Testosterone cypionate

Enclomiphene citrate

Everything in your enclomiphene protocol

Sound like you?

TRT is one of the most studied interventions in medicine

Get your protocol in 5 simple steps.

What are you trying to optimize?

Quick online intake

Comprehensive labs

Physician review

Discreet shipment

Retest at week 6 & 12

Track your testosterone, lab to lab.

Total Testosterone

What men on OPTML TRT are saying

Your typical 12-week journey on TRT

Transparent pricing. No surprises.

Side effects, told straight.

Common >10%

Less common 1-10%

Rare but serious <1%

Contraindicated

Frequently asked questions

Important safety information

Reclaim your testosterone. Without the trade-off.