Heart system

Cholesterol : HDL Ratio

Chol / HDL

The ratio of total cholesterol to HDL — a single-number cardiovascular risk score.

What is it

Cholesterol : HDL Ratio — in plain English.

This ratio is calculated by dividing total cholesterol by HDL. It captures the balance between total cholesterol burden and protective HDL in one number.

Why it's measured

What Chol / HDL can reveal.

The total cholesterol-to-HDL ratio has been used as a cardiovascular risk indicator in clinical practice and epidemiologic research.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

< 4.5 ratio

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower Chol / HDL — at a high level.

Elevated

Has been associated with elevated cardiovascular risk in published research.

Lower

Is generally considered favorable.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When Chol / HDL is typically run.

Calculated and reported automatically on most cholesterol panels.

Related markers

Often measured alongside Chol / HDL.

Measured in

Chol / HDL is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.