Heart system

Homocysteine

An amino acid byproduct linked to cardiovascular and cognitive risk in research.

What is it

Homocysteine — in plain English.

Homocysteine is an amino acid produced during methionine metabolism. Levels depend on B-vitamin status (folate, B12, B6) and genetics (MTHFR variants).

Why it's measured

What Homocysteine can reveal.

Elevated homocysteine has been associated with cardiovascular risk and cognitive decline in published research.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

< 10 μmol/L

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower Homocysteine — at a high level.

Elevated

Has been associated with elevated cardiovascular and cognitive risk in research literature, and often warrants evaluation of B-vitamin status.

Lower

Is generally considered favorable.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When Homocysteine is typically run.

Measured in advanced cardiovascular and cognitive risk assessment.

Related markers

Often measured alongside Homocysteine.

Measured in

Homocysteine is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.