Heart system

Lipoprotein (a) — Lp(a)

Lp(a)

A genetically determined lipoprotein particle linked to cardiovascular risk that most cholesterol panels never test.

What is it

Lipoprotein (a) — Lp(a) — in plain English.

Lipoprotein(a) is a particle similar to LDL but with an additional protein called apolipoprotein(a). Its levels are largely set by genetics and remain relatively stable across a lifetime.

Despite being a well-studied cardiovascular risk marker, Lp(a) is not part of the standard cholesterol panel — most people have never had it measured.

Why it's measured

What Lp(a) can reveal.

Elevated Lp(a) has been associated with increased cardiovascular risk in published research, independent of LDL cholesterol levels. Because it is genetically determined, knowing your Lp(a) once provides lasting information.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

< 30 mg/dL

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower Lp(a) — at a high level.

Elevated

Has been associated with elevated cardiovascular risk in published research, even when standard cholesterol values appear normal.

Lower

Is generally considered favorable in research literature on cardiovascular risk.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When Lp(a) is typically run.

Lp(a) is most often tested once in adulthood, since values are largely determined by genetics. Discuss with your physician based on family history and personal risk profile.

Related markers

Often measured alongside Lp(a).

Measured in

Lp(a) is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.