Heart system

Lipoprotein (a) — Lp(a)

Lp(a)

A genetically determined lipoprotein particle linked to cardiovascular risk that most cholesterol panels never test.

What is it

Lipoprotein (a) — Lp(a) — in plain English.

Lipoprotein(a) is a particle similar to LDL but with an additional protein called apolipoprotein(a). Its levels are largely set by genetics and remain relatively stable across a lifetime.

Despite being a well-studied cardiovascular risk marker, Lp(a) is not part of the standard cholesterol panel — most people have never had it measured.

Why it's measured

What Lp(a) can reveal.

Elevated Lp(a) has been associated with increased cardiovascular risk in published research, independent of LDL cholesterol levels. Because it is genetically determined, knowing your Lp(a) once provides lasting information.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

< 30 mg/dL

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

Where does your number land?

Drag to your own Lipoprotein (a) — Lp(a) result.

Educational only, not a diagnosis. Ranges vary by laboratory. See which panel includes Lipoprotein (a) — Lp(a).

What results may indicate

Higher vs. lower Lp(a) — at a high level.

Elevated

Has been associated with elevated cardiovascular risk in published research, even when standard cholesterol values appear normal.

Lower

Is generally considered favorable in research literature on cardiovascular risk.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When Lp(a) is typically run.

Lp(a) is most often tested once in adulthood, since values are largely determined by genetics. Discuss with your physician based on family history and personal risk profile.

Related markers

Often measured alongside Lp(a).

Common questions

Questions people ask about Lipoprotein (a) \u2014 Lp(a)

What is Lipoprotein (a) \u2014 Lp(a)?

Lipoprotein(a) is a particle similar to LDL but with an additional protein called apolipoprotein(a). Its levels are largely set by genetics and remain relatively stable across a lifetime.Despite being a well-studied cardiovascular risk marker, Lp(a) is not part of the standard cholesterol panel \u2014 most people have never had it measured.

Why is Lipoprotein (a) \u2014 Lp(a) measured?

It's one of the markers used to build a fuller picture of your health. On its own it tells you very little, so it's most informative when reviewed alongside related markers.

How is Lipoprotein (a) \u2014 Lp(a) tested?

It's measured from a standard blood draw at Quest or LabCorp. Lipoprotein (a) \u2014 Lp(a) is one of the markers included in the OPTML Apex Panel, where your results are read across systems and reviewed by a U.S.-licensed physician.

What should I do with my Lipoprotein (a) \u2014 Lp(a) result?

Reference ranges vary by laboratory, and a single value rarely tells the whole story. Review your result with a physician in the context of your other markers, symptoms, and history.

Not sure which panel is right for you?

Lipoprotein (a) \u2014 Lp(a) is one signal among many. Answer a few quick questions and we’ll point you to the panel that fits.

Measured in

Lp(a) is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

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160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.

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OPTML offers compounded semaglutide and tirzepatide, prescribed and overseen by U.S.-licensed physicians. Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. OPTML is not associated with, endorsed by, or affiliated with the manufacturers of FDA-approved branded weight-loss medications, and does not sell or supply those branded products. Anyone interested in an FDA-approved branded medication should consult a licensed healthcare provider or pharmacist. Individual results vary; no specific result is promised, and weight management requires ongoing medical guidance.

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