LDL particle size
The average diameter of LDL particles in your circulation.
What is it
NMR spectroscopy can measure the average size of LDL particles. Small, dense LDL particles and large, buoyant LDL particles behave differently in published research on cardiovascular risk.
Why it's measured
A predominance of small, dense LDL has been linked to elevated cardiovascular risk in research literature, often alongside insulin resistance and metabolic syndrome features.
Reference range
Standard laboratory reference
> 20.5 nm (LDL diameter)
Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.
What results may indicate
Elevated
Larger LDL particle size is generally considered more favorable in published research.
Lower
Smaller average LDL particle size has been associated with elevated cardiometabolic risk.
These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.
When it's measured
Reported as part of advanced NMR lipoprotein analysis.
Related markers
Common questions
NMR spectroscopy can measure the average size of LDL particles. Small, dense LDL particles and large, buoyant LDL particles behave differently in published research on cardiovascular risk.
It's one of the markers used to build a fuller picture of your health. On its own it tells you very little, so it's most informative when reviewed alongside related markers.
It's measured from a standard blood draw at Quest or LabCorp. NMR Lipoprotein Particle Size is one of the markers included in the OPTML Apex Panel, where your results are read across systems and reviewed by a U.S.-licensed physician.
Reference ranges vary by laboratory, and a single value rarely tells the whole story. Review your result with a physician in the context of your other markers, symptoms, and history.
NMR Lipoprotein Particle Size is one signal among many. Answer a few quick questions and we’ll point you to the panel that fits.
Measured in
A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.
Find the right panel →This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.
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