Before you start.

Most clinics will skip this. We won't. Here's exactly who qualifies for each OPTML protocol, who shouldn't be on it, and what we screen for at intake.

GLP-1 / Weight loss

Semaglutide & Tirzepatide

Eligibility, MTC/MEN2 history, pancreatitis, gallbladder, pregnancy, and the screening labs we require.

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Microdose GLP-1

Microdose GLP-1

Why microdose has a wider eligibility window, and the cases where it still isn't right.

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Men · TRT

TRT (Testosterone)

Hematocrit, PSA, fertility plans, prostate cancer history, sleep apnea, and the labs we need to see.

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Men · Fertility-sparing

Enclomiphene

Who enclomiphene is built for, why it's the fertility-sparing option, and when TRT is still the better path.

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Women · HRT

HRT (Estradiol + Progesterone)

VTE history, breast cancer, undiagnosed bleeding, migraines with aura, and the timing question that matters.

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Recovery · GH axis

Sermorelin

Active malignancy, severe illness, and why we screen IGF-1 before and during therapy.

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Cellular · NAD+

NAD+

The contraindication list is short, but the conditions matter. Histamine, pregnancy, and active cancer.

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How OPTML screens. Every protocol starts with a structured intake (10-15 min), a contraindication checklist, and either a fresh OPTML lab panel or 6-month-old labs you upload. A licensed U.S. physician reviews everything before any prescription is written. If you're not a fit, we tell you and we don't charge you.
Weight-loss medication disclaimer

OPTML offers compounded semaglutide and tirzepatide, prescribed and overseen by U.S.-licensed physicians. Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. OPTML is not associated with, endorsed by, or affiliated with the manufacturers of FDA-approved branded weight-loss medications, and does not sell or supply those branded products. Anyone interested in an FDA-approved branded medication should consult a licensed healthcare provider or pharmacist. Individual results vary; no specific result is promised, and weight management requires ongoing medical guidance.

The complete GLP-1 guide

The whole picture in one sitting: who it suits, what the labs decide, what the first year actually looks like. Every clinical claim is cited.

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guide to keeping muscle

How to protect lean mass while losing weight on a GLP-1.

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