Sermorelin is a GHRH analog, it asks your pituitary to make growth hormone, rather than supplying exogenous HGH. The risk profile is different, but the rules around active cancer and severe illness are the same.
Sermorelin is a recovery and sleep tool, not a body-recomp shortcut. The right candidate is healthy with a specific recovery deficit.
| Lab | Why |
|---|---|
| IGF-1 | The primary biomarker for GH axis. Baseline and re-test at week 12. |
| HbA1c, fasting glucose, fasting insulin | GH axis affects glucose handling. |
| CMP | Liver and kidney baseline. |
| Lipids | Cardiometabolic baseline. |
| CBC | General health. |
| TSH, free T4 | Thyroid baseline; can shift on therapy. |
| Cortisol (AM) | HPA axis baseline. |
| PSA (men ≥ 40) | Standard prostate baseline. |
Take the Find My Protocol intake. We screen IGF-1 first, if your baseline is already optimal, we'll tell you sermorelin won't move the needle.
OPTML offers compounded semaglutide and tirzepatide, prescribed and overseen by U.S.-licensed physicians. Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. OPTML is not associated with, endorsed by, or affiliated with the manufacturers of FDA-approved branded weight-loss medications, and does not sell or supply those branded products. Anyone interested in an FDA-approved branded medication should consult a licensed healthcare provider or pharmacist. Individual results vary; no specific result is promised, and weight management requires ongoing medical guidance.
The whole picture in one sitting: who it suits, what the labs decide, what the first year actually looks like. Every clinical claim is cited.
How to protect lean mass while losing weight on a GLP-1.
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