Enclomiphene is the right call for men who want to raise testosterone and preserve fertility. It's not for everyone, and it doesn't always work. Here's how we screen.
Enclomiphene is best suited for men with intact testicular function whose problem is upstream, the brain isn't sending enough LH/FSH.
| Lab | Why |
|---|---|
| Total T (AM, fasting) × 2 | Confirm low baseline. |
| Free T & SHBG | Bioavailable T. |
| LH & FSH | Confirms secondary, the key data point for enclomiphene. |
| Estradiol (sensitive) | Baseline before therapy that raises endogenous E2. |
| Prolactin | Rule out pituitary cause. |
| TSH | Rule out thyroid cause. |
| CBC, CMP, lipids | General baseline. |
| PSA (if ≥ 40) | Prostate baseline. |
That's the most common question we get. Take Find My Protocol, the algorithm and the physician will route you to the right one based on your labs and your fertility plans.
OPTML offers compounded semaglutide and tirzepatide, prescribed and overseen by U.S.-licensed physicians. Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. OPTML is not associated with, endorsed by, or affiliated with the manufacturers of FDA-approved branded weight-loss medications, and does not sell or supply those branded products. Anyone interested in an FDA-approved branded medication should consult a licensed healthcare provider or pharmacist. Individual results vary; no specific result is promised, and weight management requires ongoing medical guidance.
The whole picture in one sitting: who it suits, what the labs decide, what the first year actually looks like. Every clinical claim is cited.
How to protect lean mass while losing weight on a GLP-1.
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