Microdose GLP-1 (typically 0.10-0.25mg semaglutide or 1.25-2.5mg tirzepatide weekly) has a wider eligibility window than full-dose because the GI side effects are minimal. But the contraindications still apply.
Microdose is built for metabolic optimization, not weight loss. The right person isn't aggressively dieting, they're optimizing.
Same panel as full-dose. Microdose isn't an excuse to skip the screen.
| Lab | Why |
|---|---|
| HbA1c, fasting glucose, fasting insulin | Baseline metabolic state. |
| HOMA-IR (calculated) | The number microdose moves most. |
| CMP | Renal & liver baseline. |
| Lipid panel + apoB | Cardiometabolic baseline. |
| TSH | Thyroid mimics metabolic symptoms. |
| Lipase | Pancreatic baseline. |
| SHBG, total & free T (men) | Insulin resistance suppresses SHBG. |
It's the same molecule with a different goal. Take the Find My Protocol intake and we'll route you to microdose, full-dose, or somewhere else entirely.
OPTML offers compounded semaglutide and tirzepatide, prescribed and overseen by U.S.-licensed physicians. Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. OPTML is not associated with, endorsed by, or affiliated with the manufacturers of FDA-approved branded weight-loss medications, and does not sell or supply those branded products. Anyone interested in an FDA-approved branded medication should consult a licensed healthcare provider or pharmacist. Individual results vary; no specific result is promised, and weight management requires ongoing medical guidance.
The whole picture in one sitting: who it suits, what the labs decide, what the first year actually looks like. Every clinical claim is cited.
How to protect lean mass while losing weight on a GLP-1.
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