Inflammation system

CCP (anti-cyclic citrullinated peptide)

Anti-CCP

A more specific antibody marker for rheumatoid arthritis than RF.

What is it

CCP (anti-cyclic citrullinated peptide) — in plain English.

Anti-CCP antibodies target citrullinated proteins. They have been studied as more specific markers for rheumatoid arthritis than rheumatoid factor in published research.

Why it's measured

What Anti-CCP can reveal.

Anti-CCP has been associated with rheumatoid arthritis with higher specificity than RF in clinical research.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

< 20 U/mL

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower Anti-CCP — at a high level.

Elevated

Has been associated with rheumatoid arthritis in published research.

Lower

Is generally considered favorable.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When Anti-CCP is typically run.

Used alongside RF in evaluating rheumatoid arthritis.

Related markers

Often measured alongside Anti-CCP.

Measured in

Anti-CCP is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.