Anti-CCP
A more specific antibody marker for rheumatoid arthritis than RF.
What is it
Anti-CCP antibodies target citrullinated proteins. They have been studied as more specific markers for rheumatoid arthritis than rheumatoid factor in published research.
Why it's measured
Anti-CCP has been associated with rheumatoid arthritis with higher specificity than RF in clinical research.
Reference range
Standard laboratory reference
< 20 U/mL
Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.
Where does your number land?
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Drag to your own CCP (anti-cyclic citrullinated peptide) result.
Educational only, not a diagnosis. Ranges vary by laboratory. See which panel includes CCP (anti-cyclic citrullinated peptide).
What results may indicate
Elevated
Has been associated with rheumatoid arthritis in published research.
Lower
Is generally considered favorable.
These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.
When it's measured
Used alongside RF in evaluating rheumatoid arthritis.
Related markers
Common questions
Anti-CCP antibodies target citrullinated proteins. They have been studied as more specific markers for rheumatoid arthritis than rheumatoid factor in published research.
It's one of the markers used to build a fuller picture of your health. On its own it tells you very little, so it's most informative when reviewed alongside related markers.
It's measured from a standard blood draw at Quest or LabCorp. CCP (anti-cyclic citrullinated peptide) is one of the markers included in the OPTML Apex Panel, where your results are read across systems and reviewed by a U.S.-licensed physician.
Reference ranges vary by laboratory, and a single value rarely tells the whole story. Review your result with a physician in the context of your other markers, symptoms, and history.
CCP (anti-cyclic citrullinated peptide) is one signal among many. Answer a few quick questions and we’ll point you to the panel that fits.
Measured in
A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.
Find the right panel →This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.
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