Inflammation system

Erythrocyte Sedimentation Rate (ESR)

ESR

An older but useful marker of systemic inflammation.

What is it

Erythrocyte Sedimentation Rate (ESR) — in plain English.

The erythrocyte sedimentation rate measures how quickly red blood cells settle in a tube of anticoagulated blood. Inflammation accelerates settling.

Why it's measured

What ESR can reveal.

ESR has been used for decades as a marker of inflammation in research and clinical practice, often alongside CRP.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

Men: < 22 / Women: < 29 mm/hr

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower ESR — at a high level.

Elevated

Has been associated with active inflammation, infection, or autoimmune disease in research literature.

Lower

Is generally considered favorable.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When ESR is typically run.

Used in evaluating inflammatory conditions and autoimmune flares.

Related markers

Often measured alongside ESR.

Measured in

ESR is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
Back to all biomarkers

This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.