IGF-1
The downstream marker of growth hormone activity — and a longevity research focus.
What is it
IGF-1 is produced primarily by the liver in response to growth hormone. It reflects integrated GH activity over time and is more stable than direct GH measurement.
Why it's measured
IGF-1 has been studied in research on growth, body composition, and longevity. Both extremes (very high and very low) have been associated with health outcomes in published research.
Reference range
Standard laboratory reference
Age-dependent ng/mL
Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.
What results may indicate
Elevated
In adults, may suggest GH excess and warrants clinical evaluation. Acromegaly is a rare cause.
Lower
Has been associated with adult growth hormone deficiency in research literature.
These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.
When it's measured
Used in evaluation of GH status and is a focus of longevity research.
Related markers
Measured in
A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.
Explore the Apex Panel →This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.