Hormones system

17α-Hydroxyprogesterone

17-OHP

An adrenal steroid intermediate used to screen for certain adrenal conditions.

What is it

17α-Hydroxyprogesterone — in plain English.

17α-Hydroxyprogesterone is an intermediate in the synthesis of cortisol and androgens. It is used clinically to screen for congenital adrenal hyperplasia.

Why it's measured

What 17-OHP can reveal.

Elevated 17-OHP has been associated with adrenal enzyme deficiencies in published research.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

Context-dependent ng/dL

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower 17-OHP — at a high level.

Elevated

Warrants clinical evaluation for adrenal pathology.

Lower

Is generally not clinically significant in isolation.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When 17-OHP is typically run.

Used in adrenal evaluation, particularly when CAH or related conditions are being considered.

Related markers

Often measured alongside 17-OHP.

Measured in

17-OHP is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.