Kidney system

Total Iron Binding Capacity (TIBC)

TIBC

The total capacity of transferrin to carry iron.

What is it

Total Iron Binding Capacity (TIBC) — in plain English.

TIBC measures the total amount of iron that can be bound by transferrin in circulation. It is used alongside iron and ferritin in iron studies.

Why it's measured

What TIBC can reveal.

TIBC has been used in evaluating iron deficiency and overload in research and clinical practice.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

240 – 450 μg/dL

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower TIBC — at a high level.

Elevated

Has been associated with iron deficiency in research literature.

Lower

Has been associated with chronic inflammation or iron overload in research literature.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When TIBC is typically run.

Part of iron studies.

Related markers

Often measured alongside TIBC.

Measured in

TIBC is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.