Inflammation system

Rheumatoid Factor (RF)

RF

An antibody marker associated with rheumatoid arthritis.

What is it

Rheumatoid Factor (RF) — in plain English.

Rheumatoid factor is an autoantibody that targets the body's own immunoglobulins. Elevated levels have been associated with rheumatoid arthritis and certain other conditions.

Why it's measured

What RF can reveal.

RF has been used in clinical evaluation of rheumatoid arthritis, though it is not specific to that condition.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

< 14 IU/mL

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

Where does your number land?

Drag to your own Rheumatoid Factor (RF) result.

Educational only, not a diagnosis. Ranges vary by laboratory. See which panel includes Rheumatoid Factor (RF).

What results may indicate

Higher vs. lower RF — at a high level.

Elevated

Has been associated with rheumatoid arthritis and certain other autoimmune conditions in published research.

Lower

Is generally considered favorable.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When RF is typically run.

Used when joint symptoms suggest a rheumatologic condition.

Related markers

Often measured alongside RF.

Common questions

Questions people ask about Rheumatoid Factor (RF)

What is Rheumatoid Factor (RF)?

Rheumatoid factor is an autoantibody that targets the body's own immunoglobulins. Elevated levels have been associated with rheumatoid arthritis and certain other conditions.

Why is Rheumatoid Factor (RF) measured?

It's one of the markers used to build a fuller picture of your health. On its own it tells you very little, so it's most informative when reviewed alongside related markers.

How is Rheumatoid Factor (RF) tested?

It's measured from a standard blood draw at Quest or LabCorp. Rheumatoid Factor (RF) is one of the markers included in the OPTML Apex Panel, where your results are read across systems and reviewed by a U.S.-licensed physician.

What should I do with my Rheumatoid Factor (RF) result?

Reference ranges vary by laboratory, and a single value rarely tells the whole story. Review your result with a physician in the context of your other markers, symptoms, and history.

Not sure which panel is right for you?

Rheumatoid Factor (RF) is one signal among many. Answer a few quick questions and we’ll point you to the panel that fits.

Measured in

RF is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Find the right panel
160 biomarkers13 body systemsPhysician-reviewed
Back to all biomarkers

This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.

Weight-loss medication disclaimer

OPTML offers compounded semaglutide and tirzepatide, prescribed and overseen by U.S.-licensed physicians. Compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA. OPTML is not associated with, endorsed by, or affiliated with the manufacturers of FDA-approved branded weight-loss medications, and does not sell or supply those branded products. Anyone interested in an FDA-approved branded medication should consult a licensed healthcare provider or pharmacist. Individual results vary; no specific result is promised, and weight management requires ongoing medical guidance.

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