WBC system

Neutrophil : Lymphocyte Ratio (NLR)

NLR

A simple ratio shown in research to reflect systemic inflammatory burden.

What is it

Neutrophil : Lymphocyte Ratio (NLR) — in plain English.

The neutrophil-to-lymphocyte ratio is calculated from the CBC differential. It has been studied as a marker of systemic inflammation across many disease states in published research.

Why it's measured

What NLR can reveal.

NLR has been associated with cardiovascular risk, cancer prognosis, and chronic inflammation in published research.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

< 2.5 ratio

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower NLR — at a high level.

Elevated

Has been associated with systemic inflammation and adverse outcomes across many conditions in published research.

Lower

Generally considered favorable.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When NLR is typically run.

Calculated from CBC with differential.

Related markers

Often measured alongside NLR.

Measured in

NLR is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
Back to all biomarkers

This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.