Nutrients system

Iron Saturation %

Iron Sat

The percentage of transferrin's iron-binding capacity that is currently occupied.

What is it

Iron Saturation % — in plain English.

Iron saturation is calculated as serum iron divided by TIBC. It reflects how much of the body's iron transport capacity is currently in use.

Why it's measured

What Iron Sat can reveal.

Iron saturation has been used in evaluating iron deficiency and overload in clinical research.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

20 – 50 %

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower Iron Sat — at a high level.

Elevated

Has been associated with iron overload and hemochromatosis in research literature.

Lower

Has been associated with iron deficiency in research literature.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When Iron Sat is typically run.

Calculated from serum iron and TIBC.

Related markers

Often measured alongside Iron Sat.

Measured in

Iron Sat is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.