Nutrients system

Iron Saturation %

Iron Sat

The percentage of transferrin's iron-binding capacity that is currently occupied.

What is it

Iron Saturation % — in plain English.

Iron saturation is calculated as serum iron divided by TIBC. It reflects how much of the body's iron transport capacity is currently in use.

Why it's measured

What Iron Sat can reveal.

Iron saturation has been used in evaluating iron deficiency and overload in clinical research.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

20 – 50 %

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

Where does your number land?

Drag to your own Iron Saturation % result.

Educational only, not a diagnosis. Ranges vary by laboratory. See which panel includes Iron Saturation %.

What results may indicate

Higher vs. lower Iron Sat — at a high level.

Elevated

Has been associated with iron overload and hemochromatosis in research literature.

Lower

Has been associated with iron deficiency in research literature.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When Iron Sat is typically run.

Calculated from serum iron and TIBC.

Related markers

Often measured alongside Iron Sat.

Common questions

Questions people ask about Iron Saturation %

What is Iron Saturation %?

Iron saturation is calculated as serum iron divided by TIBC. It reflects how much of the body's iron transport capacity is currently in use.

Why is Iron Saturation % measured?

It's one of the markers used to build a fuller picture of your health. On its own it tells you very little, so it's most informative when reviewed alongside related markers.

How is Iron Saturation % tested?

It's measured from a standard blood draw at Quest or LabCorp. Iron Saturation % is one of the markers included in the OPTML Apex Panel, where your results are read across systems and reviewed by a U.S.-licensed physician.

What should I do with my Iron Saturation % result?

Reference ranges vary by laboratory, and a single value rarely tells the whole story. Review your result with a physician in the context of your other markers, symptoms, and history.

Not sure which panel is right for you?

Iron Saturation % is one signal among many. Answer a few quick questions and we’ll point you to the panel that fits.

Measured in

Iron Sat is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Find the right panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.

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