Hormones system

Estrone

E1

A weaker form of estrogen — the dominant estrogen after menopause.

What is it

Estrone — in plain English.

Estrone is a less potent estrogen than estradiol but becomes the predominant form after menopause, when ovarian estradiol production declines and estrone is produced from precursors in adipose tissue.

Why it's measured

What E1 can reveal.

Estrone is studied in research on postmenopausal hormone status and breast cancer risk.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

Context-dependent pg/mL

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower E1 — at a high level.

Elevated

Warrants clinical interpretation, particularly in research on postmenopausal women.

Lower

May reflect low overall estrogen status in research literature.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When E1 is typically run.

Measured in research and specialized hormonal evaluations.

Related markers

Often measured alongside E1.

Measured in

E1 is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.