A calculated value used to evaluate acid-base disorders.
What is it
The anion gap is calculated from sodium, chloride, and bicarbonate. It helps distinguish causes of metabolic acidosis in clinical evaluation.
Why it's measured
The anion gap has been used in research and clinical practice to evaluate acid-base disorders.
Reference range
Standard laboratory reference
8 – 12 mEq/L
Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.
What results may indicate
Elevated
Has been associated with various metabolic acidoses in research literature.
Lower
Has been associated with certain blood disorders and electrolyte issues in research literature.
These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.
When it's measured
Calculated from standard electrolyte panel.
Related markers
Measured in
A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.
Explore the Apex Panel →This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.