Longevity system

NLR (Neutrophil : Lymphocyte Ratio)

NLR

The neutrophil-to-lymphocyte ratio interpreted in a longevity context.

What is it

NLR (Neutrophil : Lymphocyte Ratio) — in plain English.

NLR is calculated from the CBC differential. In the longevity context, it reflects chronic inflammatory burden — a hallmark of biological aging studied in research literature.

Why it's measured

What NLR can reveal.

NLR has been associated with biological aging signals and mortality risk in published research.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

< 2.5 ratio

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower NLR — at a high level.

Elevated

Has been associated with elevated inflammatory burden and biological aging signals in research literature.

Lower

Generally considered favorable.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When NLR is typically run.

Calculated from CBC with differential.

Related markers

Often measured alongside NLR.

Measured in

NLR is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.