Liver system

AST : ALT Ratio

AST / ALT

The ratio of AST to ALT — provides clues about the type of liver injury.

What is it

AST : ALT Ratio — in plain English.

The AST:ALT ratio compares the two liver enzymes. Patterns of elevation differ by cause of liver injury in published research.

Why it's measured

What AST / ALT can reveal.

An AST:ALT ratio greater than 2 has been associated with alcohol-related liver injury in research literature.

Reference range

Where most laboratories draw the standard line.

Standard laboratory reference

< 1.0 ratio

Reference ranges vary by laboratory. Your individual reference range will appear on your test report and should be interpreted by your physician in the context of your overall health profile.

What results may indicate

Higher vs. lower AST / ALT — at a high level.

Elevated

Ratios > 2 have been associated with alcohol-related liver injury in research literature.

Lower

Lower ratios are commonly seen in other forms of hepatocellular injury including fatty liver disease.

These associations are general. They are not a personal diagnosis or prediction. Discuss your individual results with your physician in the context of your full health profile.

When it's measured

When AST / ALT is typically run.

Calculated when AST and ALT are both measured.

Related markers

Often measured alongside AST / ALT.

ALT (Alanine Aminotransferase)Liver systemAST (Aspartate Aminotransferase)Liver systemGGT (Gamma-Glutamyl Transferase)Liver systemAlkaline Phosphatase (ALP)Liver systemTotal BilirubinLiver systemDirect BilirubinLiver system

Measured in

AST / ALT is one of 160 biomarkers in the Apex Panel.

A complete look at your heart, hormones, metabolism, inflammation, and longevity systems — drawn at Quest or LabCorp, reviewed by a U.S.-licensed physician.

Explore the Apex Panel →
160 biomarkers13 body systemsPhysician-reviewed
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This information is for general educational purposes only and is not medical advice. Lab results alone are not intended to diagnose, treat, or cure any condition and do not replace the advice of a healthcare provider. OPTML does not offer medical advice, a diagnosis, medical treatment, or any form of medical opinion.