Comparison · Updated April 2026

OPTML vs. Henry Meds: cheaper GLP-1s + everything Henry doesn't carry.

OPTML is $68/mo cheaper on semaglutide and $100/mo cheaper on tirzepatide than Henry Meds, and adds TRT, enclomiphene, comprehensive labs, and physician (not NP) oversight that Henry doesn't offer. If GLP-1 is the only thing you'll ever need, both work. If you're optimizing anything else, this comparison is one-sided.

Cheaper on every GLP-1 3 protocols Henry doesn't offer Physician-led care · Labs available
Try OPTML, Start $0 consult
LegitScript CertifiedLegitScript CertifiedHealthcare Merchant

Head-to-head at a glance

What you actually get for your monthly fee.

FeatureOPTMLHenry Meds
Compounded Semaglutide✓ $249/mo annual, $98 cheaper✗ ~$297/mo
Compounded Tirzepatide✓ $349/mo annual, $150 cheaper✗ ~$449/mo
Testosterone Replacement Therapy✓ $199/mo annual, labs and dose tuning included✗ Not offered
Enclomiphene (fertility-preserving T)✓ $129/mo, preserves fertility, oral capsule✗ Not offered
Comprehensive blood panels✓ Included on most plans✗ Not included
Physician-supervised protocols✓ U.S.-licensed physician sign-off✗ Primarily NP-led
Follow-up labs at 90 days✓ Standard on annual plans✗ Not standard
Longevity protocols (peptides, NAD+, advanced testing)✓ Core focus✗ Weight-loss focused
NAD+ therapy✓ Full injection + nasal protocolsLimited offering
Bioidentical HRT for women (estradiol + progesterone)✓ Starting at $199/mo, see HRT page →✗ Not offered
Microdose GLP-1 (sub-clinical sema/tirz)✓ Sema $199/mo · Tirz $299/mo, see microdose page →✗ Not offered
Sermorelin (GHRH peptide for sleep, recovery, body comp)✓ $189/mo, see sermorelin page →Limited offering
Unlimited messaging with care team✓ 24-hour response time✓ Included
HSA / FSA eligible✓ Yes✓ Yes

Henry Meds is GLP-1 only. OPTML is GLP-1s at a lower price plus the rest of the optimization stack, without paying more.

Where each platform actually wins

Quick read for anyone comparison-shopping.

optml, pick this if
  • You want the cheapest cash-pay GLP-1 ($68-$100/mo less than Henry)
  • You want TRT or enclomiphene (Henry doesn't offer either)
  • You want labs and 90-day follow-up included, not unavailable
  • You want physician sign-off, not NP-only
  • NAD+, peptides, or longevity work matters to you
Henry Meds, pick this if
  • You only want a compounded GLP-1, paying $68-$100/mo more
  • You don't want labs, follow-up testing, or hormone work
  • NP-led intake is fine; you're not optimizing complex cases
Bottom line

For nearly every patient, OPTML wins. Cheaper GLP-1s, plus TRT, enclomiphene, NAD+, and labs Henry simply doesn't offer. The only edge case: if you've already gotten what you need from Henry's NP-led GLP-1 path and don't want anything else.

Frequently asked questions

No, OPTML is cheaper across the board on GLP-1s. OPTML's annual semaglutide plan is $249/mo vs Henry's ~$297/mo (a $68/mo difference). Tirzepatide is $349/mo vs Henry's ~$449/mo ($100/mo difference). And OPTML includes baseline labs and a 90-day follow-up Henry doesn't offer, so the all-in 12-month cost gap is even larger.
Henry Meds is GLP-1-and-peptide focused with a streamlined NP-led intake. OPTML carries a deeper stack, TRT, enclomiphene, NAD+ in multiple formats, integrated lab panels, and physician-supervised hormone work, plus the GLP-1s.
Henry Meds care is primarily nurse-practitioner led. OPTML protocols are designed and supervised by licensed physicians, with NP and PA support. Both models are legal; the depth of clinical oversight differs.
Yes. Share your prior labs, current dose, and pharmacy info during intake, most patients keep their current titration and we add the missing labs and follow-up cadence.
Yes. Both platforms use 503A compounding pharmacies for compounded semaglutide and tirzepatide. OPTML adds physician oversight on titration and a follow-up lab at 90 days.

Compare pricing for your own plan

Start a free OPTML consultation to see what's recommended for you, no commitment.

Start your consultation